Poly(ADP-ribose) glycohydrolase | |||||||||
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Identifiers | |||||||||
EC no. | 3.2.1.143 | ||||||||
CAS no. | 9068-16-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) is an enzyme. This enzyme catalyses the following chemical reaction
- hydrolyses poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose
Specific to (1''-2') linkage of ribose-ribose bond of poly(ADP-ribose).
References
- Miwa M, Sugimura T (October 1971). "Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-robose) by a calf thymus extract". The Journal of Biological Chemistry. 246 (20): 6362–4. PMID 4331388.
- Lin W, Amé JC, Aboul-Ela N, Jacobson EL, Jacobson MK (May 1997). "Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase". The Journal of Biological Chemistry. 272 (18): 11895–901. doi:10.1074/jbc.272.18.11895. PMID 9115250.
External links
- Poly(ADP-ribose)+glycohydrolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Hydrolase: sugar hydrolases (EC 3.2) | |||||||
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3.2.1: Glycoside hydrolases |
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3.2.2: Hydrolysing N-Glycosyl compounds |
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