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Streptogramin

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(Redirected from Streptogramins) Class of natural cyclic peptide antibiotics produced by certain subspecies of Streptomyces

Streptogramins are a class of antibiotics.

Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A and streptogramin B.

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References

  1. University of Leeds: Antimicrobial Chemotherapy Archived 2007-04-28 at the Wayback Machine
  2. "Streptogramin - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2024-10-06.
  3. Boucher, H. W.; Talbot, G. H.; Bradley, J. S.; Edwards, J. E.; Gilbert, D; Rice, L. B.; Scheld, M; Spellberg, B; Bartlett, J (2009). "Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America". Clinical Infectious Diseases. 48 (1): 1–12. doi:10.1086/595011. PMID 19035777.
Antibacterials that inhibit protein synthesis (J01A, J01B, J01F, J01G, QJ01XQ)
30S
Aminoglycosides
(initiation inhibitors)
-mycin (Streptomyces)
-micin (Micromonospora)
other
Tetracycline antibiotics
(tRNA binding)
Tetracyclines
Glycylcyclines
50S
Oxazolidinone
(initiation inhibitors)
Peptidyl transferase
Amphenicols
MLS (transpeptidation/translocation)
Macrolides
Ketolides
Lincosamides
Streptogramins
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