Majocchi's disease - Misplaced Pages

Not to be confused with Majocchi's granuloma. Medical condition

Majocchi's disease

Purpura annularis telangiectodes

Majocchi's disease, also known as Purpura annularis telangiectodes of Majocchi is a not-well-recognized and uncommon skin condition characterized by purple/bluish-red 1- to 3-cm annular patches composed of dark red telangiectases with petechiae. It is one of a group of disorders referred to as pigmented purpuric dermatosis that all occur as a result of vascular inflammation and pigment deposition.

Signs and symptoms

Majocchi's disease is characterized by punctuate reddish-brown macules and symmetrical, annular patches, with a tendency toward the lower extremities.

Treatment

Majocchi's disease is a chronic condition for which there is no cure. It often follows a recurrent course of alternating improvement and flares. There are treatments available to help improve the symptoms for some individuals, but responses vary. Some of these treatments include the application of topical steroids and ultraviolet therapy. The use of narrowband UVB and psoralen have shown to be effective treatments for some patients with pigmented purpuric dermatoses.

References

Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
^ Dhali, Tapan Kumar; Chahar, Monica; Haroon, Mohammad Asad (2015). "Phototherapy as an effective treatment for Majocchi's disease - Case report". Anais Brasileiros de Dermatologia. 90 (1): 96–99. doi:10.1590/abd1806-4841.20153067. ISSN 0365-0596. PMC 4323703. PMID 25672304.

Pigmentation disorders/Dyschromia

Hypo-/
leucism

Loss of
melanocytes

Vitiligo	Quadrichrome vitiligo Vitiligo ponctué
Syndromic	Alezzandrini syndrome Vogt–Koyanagi–Harada syndrome
Melanocyte development	Piebaldism Waardenburg syndrome Tietz syndrome

Loss of melanin/
amelanism

Albinism	Oculocutaneous albinism Ocular albinism in humans
Melanosome transfer	Hermansky–Pudlak syndrome Chédiak–Higashi syndrome Griscelli syndrome Elejalde syndrome Griscelli syndrome type 2 Griscelli syndrome type 3
Other	Cross syndrome ABCD syndrome Albinism–deafness syndrome Idiopathic guttate hypomelanosis Phylloid hypomelanosis Progressive macular hypomelanosis

Leukoderma w/o
hypomelanosis

Ungrouped

Hyper-

Melanin/
Melanosis/
Melanism

Reticulated	Dermatopathia pigmentosa reticularis Pigmentatio reticularis faciei et colli Reticulate acropigmentation of Kitamura Reticular pigmented anomaly of the flexures Naegeli–Franceschetti–Jadassohn syndrome Dyskeratosis congenita X-linked reticulate pigmentary disorder Galli–Galli disease Revesz syndrome
Diffuse/ circumscribed	Lentigo/Lentiginosis: Lentigo simplex Liver spot Centrofacial lentiginosis Generalized lentiginosis Inherited patterned lentiginosis in black persons Ink spot lentigo Lentigo maligna Mucosal lentigines Partial unilateral lentiginosis PUVA lentigines Melasma Erythema dyschromicum perstans Lichen planus pigmentosus Café au lait spot Poikiloderma (Poikiloderma of Civatte Poikiloderma vasculare atrophicans) Riehl melanosis
Linear	Incontinentia pigmenti Scratch dermatitis Shiitake mushroom dermatitis
Other/ ungrouped	Acanthosis nigricans Freckle Familial progressive hyperpigmentation Pallister–Killian syndrome Periorbital hyperpigmentation Photoleukomelanodermatitis of Kobori Postinflammatory hyperpigmentation Transient neonatal pustular melanosis

Other
pigments

Iron	Hemochromatosis Iron metallic discoloration Pigmented purpuric dermatosis Schamberg disease Majocchi's disease Gougerot–Blum syndrome Doucas and Kapetanakis pigmented purpura/Eczematid-like purpura of Doucas and Kapetanakis Lichen aureus Angioma serpiginosum Hemosiderin hyperpigmentation
Other metals	Argyria Chrysiasis Arsenic poisoning Lead poisoning Titanium metallic discoloration
Other	Carotenosis Tar melanosis

Dyschromia