NLRP13 - Misplaced Pages

Protein-coding gene in the species Homo sapiens

NLRP13

Identifiers

NLRP13, CLR19.7, NALP13, NOD14, PAN13, NLR family, pyrin domain containing 13, NLR family pyrin domain containing 13

External IDs

OMIM: 609660; HomoloGene: 65313; GeneCards: NLRP13; OMA:NLRP13 - orthologs

Gene location (Human)

Chr.	Chromosome 19 (human)

Band	19q13.43	Start	55,891,699 bp
Band	19q13.43	End	55,932,336 bp

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

oocyte

secondary oocyte

epithelium of colon

bone marrow cells

testicle

tonsil

skeletal muscle tissue

urinary bladder

liver

breast

n/a

More reference expression data

BioGPS

n/a

Orthologs

Species

Human

Mouse

Entrez


126204


n/a

Ensembl


ENSG00000173572


n/a

UniProt


Q86W25


n/a

RefSeq (mRNA)


NM_176810 NM_001321057


n/a

RefSeq (protein)


NP_001307986 NP_789780


n/a

Location (UCSC)

Chr 19: 55.89 – 55.93 Mb

n/a

PubMed search

n/a

Wikidata

View/Edit Human

NLRP13, short for NOD-like receptor family pyrin domain containing 13, is an intracellular protein of mammals. It is also known as NALP13, NOD14, PAN13, and CLR19.7, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors. The function of NLRP13 is currently unknown.

References

^ GRCh38: Ensembl release 89: ENSG00000173572 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Tschopp J, Martinon F, Burns K (February 2003). "NALPs: a novel protein family involved in inflammation". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287. S2CID 31417018.

Enjuanes A, Benavente Y, Bosch F, et al. (2008). "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia". Cancer Res. 68 (24): 10178–86. doi:10.1158/0008-5472.CAN-08-2221. PMID 19074885.
Inohara N, Nuñez G (2003). "NODs: intracellular proteins involved in inflammation and apoptosis". Nat. Rev. Immunol. 3 (5): 371–82. doi:10.1038/nri1086. PMID 12766759. S2CID 8088987.

v t e NOD-like receptor family
CARD domain containing	NOD1/NLRC1 NOD2/NLRC2 NLRC3 NLRC4 NLRC5
Pyrin domain containing	NLRP1 NLRP2 NLRP3 NLRP4 NLRP5 NLRP6 NLRP7 NLRP8 NLRP9 NLRP10 NLRP11 NLRP12 NLRP13 NLRP14
Apoptosis inhibitory protein	NAIP
Family member X1	NLRX1

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