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Nacolomab tafenatox

Schematic image of nacolomab tafenatox: VH, VL: variable (antigen binding) domains of antibody fragment CH1, CL: constant domains of antibody fragment SAg: enterotoxin A (acting as a superantigen)
Monoclonal antibody
Type	Fab fragment
Source	Mouse
Target	colorectal tumor antigen C242
Clinical data
ATC code	none
Identifiers
CAS Number	150631-27-9
ChemSpider	none
UNII	PRC47TA1NU
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Nacolomab tafenatox is a mouse monoclonal antibody. The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).

See also

• Naptumomab estafenatox, a drug with a similar chemical structure and mechanism

References

1. ^ "Recommended INN List: Nacolomab tafenatox" (PDF). WHO Drug Information. 9 (3): 182. 1995. Archived from the original (PDF) on 23 February 2012.
2. Alpaugh RK, Weiner LM, Persson B, Persson R, Dohlsten M, Kalland T (1997). "Nacolomab Tafenatox". Drugs of the Future. 22 (11): 1226–30.

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