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NCAPD3

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Protein-coding gene in the species Homo sapiens
NCAPD3
Identifiers
AliasesNCAPD3, CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6, non-SMC condensin II complex subunit D3, MCPH22
External IDsOMIM: 609276; MGI: 2142989; HomoloGene: 41021; GeneCards: NCAPD3; OMA:NCAPD3 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)
Chromosome 11 (human)Genomic location for NCAPD3Genomic location for NCAPD3
Band11q25Start134,150,113 bp
End134,225,504 bp
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)
Chromosome 9 (mouse)Genomic location for NCAPD3Genomic location for NCAPD3
Band9|9 A4Start26,941,471 bp
End27,006,611 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • secondary oocyte

  • ventricular zone

  • gonad

  • prostate

  • ganglionic eminence

  • testicle

  • stromal cell of endometrium

  • right lobe of liver

  • left testis
Top expressed in
  • hand

  • Gonadal ridge

  • Paneth cell

  • primary oocyte

  • thymus

  • dermis

  • human fetus

  • superior cervical ganglion

  • neural layer of retina

  • abdominal wall
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23310

78658

Ensembl

ENSG00000151503

ENSMUSG00000035024

UniProt

P42695

Q6ZQK0

RefSeq (mRNA)

NM_015261
NM_001372065
NM_001372068
NM_001372069
NM_001372070

NM_178113
NM_001382847

RefSeq (protein)

NP_056076
NP_001358994
NP_001358997
NP_001358998
NP_001358999

NP_835214
NP_001369776

Location (UCSC)Chr 11: 134.15 – 134.23 MbChr 9: 26.94 – 27.01 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene. CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000151503Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000035024Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (December 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 1 (5): 223–229. doi:10.1093/dnares/1.5.223. PMID 7584044.
  6. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (June 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
  7. Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–121. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007. S2CID 18811084.
  8. "NCAPD3 non-SMC condensin II complex, subunit D3". National Center for Biotechnology Information. Retrieved June 10, 2012.

Further reading

Structures of the cell nucleus / nuclear protein
Envelope (membrane)/
nuclear lamina
Nucleolus
Other
SMC protein:
Transition nuclear protein:
see also nucleus diseases


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