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KRT74

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Protein-coding gene in humans

keratin 74
Identifiers
Symbol	KRT74
NCBI gene	121391
HGNC	28929
RefSeq	NM_175053
Other data
Locus	Chr. 12 q13.13

KRT74 is a keratin gene.

Mutations in KRT74 cause hair and nail ectodermal dysplasia.

References

Raykova D, Klar J, Azhar A, Khan TN, Malik NA, Iqbal M, Tariq M, Baig SM, Dahl N (2014). "Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis". PLOS ONE. 9 (4): e93607. Bibcode:2014PLoSO...993607R. doi:10.1371/journal.pone.0093607. PMC 3979697. PMID 24714551.

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Proteins of the cytoskeleton

Human

Microfilaments
and ABPs

A1
A2
B
C1
G1
G2

I
- MYO1A
- MYO1B
- MYO1C
- MYO1D
- MYO1E
- MYO1F
- MYO1G
- MYO1H)
II
- MYH1
- MYH2
- MYH3
- MYH4
- MYH6
- MYH7
- MYH7B
- MYH8
- MYH9
- MYH10
- MYH11
- MYH13
- MYH14
- MYH15
- MYH16
III
- MYO3A
- MYO3B
V
- MYO5A
- MYO5B
- MYO5C
VI
- MYO6
VII
- MYO7A
- MYO7B
IX
- MYO9A
- MYO9B
X
- MYO10
XV
- MYO15A
XVIII
- MYO18A
- MYO18B
LC
- MYL1
- MYL2
- MYL3
- MYL4
- MYL5
- MYL6
- MYL6B
- MYL7
- MYL9
- MYLIP
- MYLK
- MYLK2
- MYLL1

Other

Actinin
- 1
- 2
- 3
- 4
Arp2/3 complex
actin depolymerizing factors
- Cofilin
  - 1
  - 2
- Destrin
Gelsolin
Profilin
- 1
- 2
Titin

Other

Intermediate
filaments

Type 1/2
(Keratin,
Cytokeratin)

Epithelial keratins (soft alpha-keratins)	type I/chromosome 17 9 10 12 13 14 15 16 17 19 20 chromosome 12 18 none 21 type II/chromosome 12 1 2A 3 4 5 6A 6B 6C 7 8
Hair keratins (hard alpha-keratins)	type I/chromosome 17 31 32 33A 33B 34 35 36 37 38 type II/chromosome 12 81 82 83 84 85 86
Ungrouped alpha	chromosome 17 23 24 25 26 27 28 39 40 chromosome 12 71 72 73 74 75 76 77 78 79 80
Not alpha	Beta-keratin

Type 3

Type 4

Type 5

Microtubules
and MAPs

Tubulins	TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBB TUBB1 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4Q TUBB6 TUBB8 TUBG1 TUBG2 TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6 TUBD1 TUBE1
MAPs	EB1 EB2 EB3 MAP1A MAP1B MAP2 MAP4
Kinesins	KIF1A KIF1B KIF2A KIF2C KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF5C KIF6 KIF7 KIF9 KIF11 KIF12 KIF13A KIF13B KIF14 KIF15 KIF16B KIF17 KIF18A KIF18B KIF19 KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF24 KIF25 KIF26A KIF26B KIF27 KIFC1 KIFC2 KIFC3
Dyneins	axonemal: DNAH1 DNAH2 DNAH3 DNAH5 DNAH6 DNAH7 DNAH8 DNAH9 DNAH10 DNAH11 DNAH12 DNAH13 DNAH14 DNAH17 DNAI1 DNAI2 DNALI1 DNAL1 DNAL4 cytoplasmic: DYNC1H1 DYNC2H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNC2LI1 DYNLL1 DYNLL2 DYNLRB1 DYNLRB2 DYNLT1 DYNLT3
Microtubule organising proteins	CAMSAP1 CAMSAP2 CAMSAP3 Centrin 1 Centrin 2 Centrin 3 PCM1
Microtubule severing proteins	Katanin Spastin
Other	Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3

Dystrophin
- Dystroglycan
Utrophin
Ankyrin
- ANK1
- ANK2
- ANK3
Spectrin
- SPTA1
- SPTAN1
- SPTB
- SPTBN1
- SPTBN2
- SPTBN4
- SPTBN5

Other

Plakins
- Corneodesmosin
- Desmoplakin
- Dystonin
- Envoplakin
- MACF1
- Periplakin
- Plectin
Talin
- TLN1
Vinculin
Plakophilin
- PKP1
- PKP2
ACF7
PLEKHA7

Nonhuman

See also: cytoskeletal defects

This article on a gene on human chromosome 12 is a stub. You can help Misplaced Pages by expanding it.

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