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KRT80
Identifiers
Aliases	KRT80, KB20, keratin 80
External IDs	OMIM: 611161; MGI: 1921377; HomoloGene: 66610; GeneCards: KRT80; OMA:KRT80 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.13 Start 52,168,996 bp End 52,192,014 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15 F1|15 Start 101,245,325 bp End 101,268,043 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen skin of arm skin of leg skin of thigh amniotic fluid skin of hip gums gingival epithelium vulva human penis Top expressed in lip esophagus skin of external ear skin of back right lung granulocyte right lung lobe molar external naris conjunctival fornix More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding structural molecule activity Cellular component cytoplasm desmosome keratin filament intermediate filament cytosol intermediate filament cytoskeleton Biological process keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 144501 74127 Ensembl ENSG00000167767 ENSMUSG00000037185 UniProt Q6KB66 Q0VBK2 RefSeq (mRNA) NM_001081492 NM_182507 NM_028770 RefSeq (protein) NP_001074961 NP_872313 NP_083046 Location (UCSC) Chr 12: 52.17 – 52.19 Mb Chr 15: 101.25 – 101.27 Mb PubMed search
Wikidata
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Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.

Function

Keratins, such as KRT80, are filament proteins that make up one of the major structural fibers of epithelial cells.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000167767 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000037185 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
6. "Entrez Gene: KRT80 keratin 80".
7. Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J (March 2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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