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Fluprednidene

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Chemical compound Not to be confused with Fluprednidene acetate. Pharmaceutical compound
Fluprednidene
Clinical data
Other namesFluprednylidene; 9α-Fluoro-11β,17α,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • (8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopentaphenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.016.901 Edit this at Wikidata
Chemical and physical data
FormulaC22H27FO5
Molar mass390.451 g·mol
3D model (JSmol)
SMILES
  • C12C(3((1CC(=C)2(C(=O)CO)O)CCC4=CC(=O)C=C43C)F)O
InChI
  • InChI=1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1
  • Key:YVHXHNGGPURVOS-SBTDHBFYSA-N

Fluprednidene, also known as fluprednylidene, is a synthetic glucocorticoid corticosteroid which was never marketed. An acetate ester of fluprednidene, fluprednidene acetate, in contrast, has been marketed.

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 570–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 463–. ISBN 978-3-88763-075-1.
  3. ^ Challener CA (1 December 2001). Chiral Drugs. Wiley. p. 490. ISBN 978-0-566-08411-9.


Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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